myBaits – targeted next-generation sequencing kits for any organism
Next-generation sequencing (NGS) platforms have revolutionized the scale and efficiency of genetics studies. Our high-quality myBaits hybridization capture kits—and companion Library Prep kits— let you harness the full power of NGS to sequence any known or novel mutation while dramatically reducing per-sample sequencing costs.
Our myBaits and library prep kits can be easily integrated into your own research workflows—or paired with our customizable Sequencing or Bioinformatics services for a seamless NGS solution.
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Product overview
By focusing sequencing efforts on specific regions of interest, targeted sequencing technology can increase the scale and efficiency of next-generation sequencing (NGS) research by orders of magnitude. Using myBaits hybridization capture kits in any NGS workflow can lower your sequencing costs by reducing irrelevant data from your analysis.
- Cost savings—Focus your NGS on targets of interest, only pay for data you need.
- Superior performance—Optimized chemistry and protocol for high, even coverage.
- Probe design service—Includes project and panel design assistance from our scientists.
- Open platform—Compatible with any NGS library preparation system.
- Scalable—Different panel and kit sizes available for any project scale.
- Complete solution—Convenient kits include hybridization and wash reagents.
Applications
Target enrichment via hybridization-based capture is a powerful and versatile NGS tool. myBaits kits have been used successfully in thousands of research projects for a wide variety of applications, including:
- Variant/marker discovery
- Gene/exon/SNP re-sequencing
- Microbes / pathogens
- Metagenomics
- Species identification
- Genotyping
- Degraded and ancient DNA
- Phylogenetics and evolutionary biology
myBaits Custom Kits
For more than a decade, the myBaits® team has provided customized, high-performance hybridization capture kits for human, plant, animal, bacterial, and viral research from a wide variety of sample substrates and qualities. myBaits Custom Hybridization Capture Kits are perfect for new or expert users, offering a simple protocol that delivers consistent and reproducible results.
- Reduce your per-sample sequencing costs while increasing the accuracy and power of your data analysis.
- Hybridization capture of NGS library molecules using biotinylated baits provides the best combination of ease, efficiency, and cost-effectiveness.
- Our proprietary oligo synthesis platform provides flexible production of high-quality baitsets for any project size.
- myBaits kits can be easily integrated into your own research workflow, or in our customizable Sequencing or Bioinformatics services.
myBaits Predesigned Kits
myBaits target capture kits provide pools of biotinylated probes plus reagents for highly efficient, scalable targeted sequencing on any NGS platform. They have been used successfully in thousands of research projects on a wide variety of genome types (e.g. animals, plants, and microbes) and DNA/RNA sources (e.g. fresh, degraded, and environmental).
Our myBaits Expert Predesigned Kits are a select collection of baitsets that have been designed through collaboration with expert researchers and Daicel Arbor scientists. From the vast body of published literature using myBaits Custom kits, our team have curated a growing collection of Community Panels whose original designers have generously agreed to make available for other researchers through Daicel Arbor Biosciences to accelerate their discovery.
We continually expand our portfolio with high-quality offerings, so check back often or contact us if there is a specific panel that you recommend we consider for our catalog.
myBaits kits can be easily integrated into your own laboratory workflow, or let us handle everything with our customizable Sequencing or Bioinformatics services.
myBaits kits are for research use only and are not validated for diagnostic or therapeutic purposes.
Technology
Enhance your sequencing efficiency with myBaits
Daicel Arbor’s proprietary flexible and customizable oligo pool synthesis technology powers our myBaits hybridization capture kits. In-solution hybridization capture uses pools of thousands of custom biotinylated oligonucleotide molecules to selectively extract specific regions of interest in an NGS library prior to sequencing. This dramatically increases sequencing efficiency, minimizing irrelevant data from your analysis.
Product selector – myBaits Custom Kits
To help select the correct myBaits Custom Kit for your project, consult the table below.
Purpose | Research | Sample Types | Product |
---|---|---|---|
Enriching NGS libraries built from extracted DNA | Gene or exon resequencing, novel variant discovery, phylogenetics, transgene detection, and more | Genomic DNA, metagenomic DNA, environmental DNA, ancient DNA, museum DNA, FFPE samples, cfDNA, ctDNA, plant, animal, virus, bacteria, human, and more | myBaits DNA-Seq Learn More |
Enriching NGS libraries built from extracted RNA/cDNA | Gene expression profiling and/or rare transcript detection | Transcriptomic RNA, environmental RNA, viral or pathogen RNA, human, plant, animal, bacteria, degraded RNA, and more | myBaits RNA-Seq Learn More |
Enriching NGS libraries built from bisulfite- or enzymatic-converted NGS libraries | Epigenetic methylation sequencing | Bisulfite- or enzymatic-converted DNA for methylation sequencing | myBaits Methyl-Seq Learn More |
Product selector – myBaits Predesigned Kits
To help select the correct myBaits Predesigned Kit for your project, consult the table below.
Purpose | Categories | Product |
---|---|---|
Curated collection of myBaits Custom panels from the published literature | Available options for:
|
myBaits Custom Community Panels Learn More |
Expert-designed probesets suitable for many popular research applications | Available options for:
|
myBaits Expert Predesigned Kits Learn More |
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Please do not hesitate to reach out to me if you have technical questions or need price estimates for any of our products and services. We are just a phone call away!